Going with one time here, he is coming of a long layoff and the first loss of his career, but I think he has a lot to prove and enough left in the tank to win this fight. He will have more than enough motivation to win this fight, he wants to win the championship again and make a big payday (or 2).
I think the time off could work to his advantage, it gives him a chance to rest his body and get his mind right.
His opponent is also coming off of a loss, but he was stopped by a lightweight.
Thurman has fought the better competition and even though he lost to Manny, he came back from a 1st round knockdown to almost win the fight.
I expect a good fight here, both fighters with be focused and ready to fight.
Thurman by decision, good luck everyone